Symbol Name ID |
Cdk4
cyclin dependent kinase 4 MGI:88357 |
Darker colors indicate more annotations |
Human Phenotypes | Type II diabetes mellitus |
Disease(s) Associated with CDK4 | |
type 2 diabetes mellitus |
Mouse Phenotypes | abnormal pancreatic islet morphology |
increased pancreatic beta cell number |
small pancreatic islets |
decreased lactotroph cell number |
adenohypophysis hypoplasia |
abnormal corpus luteum morphology |
small ovary |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
abnormal Sertoli cell morphology |
small seminiferous tubules |
decreased Leydig cell number |
absent Leydig cells |
increased Leydig cell number |
decreased testis weight |
small testis |
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Availability | Mouse Genotype | ||||||||||||||||
Cdk4tm1.1Bbd/Cdk4tm1.1Bbd | |||||||||||||||||
Cdk4tm1Bbd/Cdk4tm1Bbd | |||||||||||||||||
Cdk4tm1Kiyo/Cdk4tm1Kiyo | |||||||||||||||||
Cdk4tm1.1Bbd/Cdk4+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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