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Symbol
Name
ID
Cdk4
cyclin dependent kinase 4
MGI:88357
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Type II diabetes mellitus
Disease(s) Associated with CDK4
type 2 diabetes mellitus

Mouse Phenotypes
abnormal pancreatic islet morphology
increased pancreatic beta cell number
small pancreatic islets
decreased lactotroph cell number
adenohypophysis hypoplasia
abnormal corpus luteum morphology
small ovary
abnormal testis morphology
abnormal seminiferous tubule morphology
abnormal Sertoli cell morphology
small seminiferous tubules
decreased Leydig cell number
absent Leydig cells
increased Leydig cell number
decreased testis weight
small testis
Availability Mouse Genotype
Cdk4tm1.1Bbd/Cdk4tm1.1Bbd
Cdk4tm1Bbd/Cdk4tm1Bbd
Cdk4tm1Kiyo/Cdk4tm1Kiyo
Cdk4tm1.1Bbd/Cdk4+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory